The development of a facile tandem Wolff/Cope rearrangement for the synthesis of fused carbocyclic skeletons.
نویسندگان
چکیده
A set of mild processes for the conversion of vinyl cyclopropyl diazo ketones to highly functionalized cycloheptadienones and vinyl cyclopentenones by use of a target-inspired tandem Wolff/Cope rearrangement sequence is described. A divergent reaction course of the vinyl cyclopropyl diazo ketone substrates under sono- or photochemical activation provides good to excellent yields (55-98%) of the product cycloheptadienones and vinyl cyclopentenones.
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ورودعنوان ژورنال:
- Journal of the American Chemical Society
دوره 125 45 شماره
صفحات -
تاریخ انتشار 2003